ABSTRACT

In recent years variety of proinflammatory and anti-inflammatory cytokines have been identified which are involved in pathogenesis and progression of rheumatoid arthritis (RA) in various extent. Macrophage derived cytokines and T cell cytokines having crucial role in the pathogenesis of RA. It is well established that imbalance between proinflammatory and antiinflammatory cytokines triggers induction of autoimmunity and RA. However exact cytokine pathways that responsible for induction of inflammation and cartilage destruction are not fully cleared. The aim of this review article is to provide a detailed information about the role of various macrophage derived cytokines in the pathogenesis and progression of RA. Keywords: Rheumatoid arthritis, cytokine, macrophage, cartilage
Publication date: 01/09/2021

https://ijbpas.com/pdf/2021/September/MS_IJBPAS_2021_5683.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.9.5683