ABSTRACT

Background: Antipsychotics are the primary therapeutic intervention in the treatment of patients with psychiatric disorders. Prescribing trends of antipsychotics has modified with accessibility of atypical antipsychotics. The assessment of current life skills, quality of life, medication adherence of the patient and subsequent intervention becomes necessary forcomprehensive rehabilitation of people with mental illness. Hence continuous studies on antipsychotics are needed to provide most upgraded, effective and rational treatment of psychoses. Methods: A prospective observational study of patients receiving antipsychotics was carried out in Psychiatry Department of Pushpagiri Medical College Hospital, Thiruvalla for a periodof six months. All relevant data of the enrolled patients was collected from various data sources and was documented in a suitably designed data collection forms to evaluate the pattern of medication use, ADL and IADL, quality of life and medication adherence. Results: A total of 91 patients was enrolled in study. Male predominance (58.24%) was observed in the study. Among typical antipsychotics, Chlorpromazine (60%) and among atypical antipsychotics,Risperidone (45.07%) was most commonly prescribed antipsychotic. Higher inclination towards atypical antipsychotics was observed than typical antipsychotics. The WHO Core Prescribing indications corresponded with the optimal values, suggesting rational drug therapy. The quality of life of patients after taking antipsychotics was improved by score of 87.187. Medication adherence was improved by 51.65% after patient counselling. Conclusion: Clinical Pharmacist-led collaborative counselling treatment have helped the patients in understanding about their condition and developing a positive attitude towards their disorder and reduced the risk of relapse. Keywords: Antipsychotics, Prescribing pattern, Activities of daily living, Instrumental activities of daily living, Quality of life, Medication adherence
Publication date: 01/03/2026

https://ijbpas.com/pdf/2026/March/MS_IJBPAS_2026_9971.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.3.9971