ABSTRACT

Hypertension, also known as high blood pressure, is a chronic medical condition in which the force of the blood against the walls of the arteries is consistently too high. Efonidipine hydrochloride ethanoate is a calcium channel blocker, that inhibits both the L and T-type calcium channels, it exhibits an antihypertensive effect. Chlorthalidone is a thiazide-like diuretic. Chlorthalidone improves blood pressure and swelling by preventing water absorption from the kidneys by inhibiting Na+/Cl- in the distal convoluted tubule cells in the kidney. This review consolidates the analytical methods, for the estimation of Efonidipine Hydrochloride Ethanoate and Chlorthalidone individually or in combination with other drugs. Various analytical techniques like HPLC, UV, HPTLC, and LC-MS methods have been reported for the estimation of the prescribed drugs. Keywords: Hypertension, Efonidipine Hydrochloride Ethanoate, Chlorthalidone, Analytical methods
Publication date: 01/03/2026

https://ijbpas.com/pdf/2026/March/MS_IJBPAS_2026_9948.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.3.9948