AN OPEN LABEL, SINGLE ARM CLINICAL STUDY ON THE COMBINED EFFECTIVENESS OF LODHRADI KASHAYA AND NAVAKA GUGGULU IN TYPE 2 DIABETES MELLITUS Authors: Bangre SM , BANGRE PM, MUTTAPPA T AND HEGDE PL
ABSTRACT
Background: Diabetes mellitus (DM) is a metabolic disorder characterized by persistent
hyperglycaemia either due to less production of insulin or resistance of insulin receptors.
Globally 537 million individuals are living with Diabetes and is predicted to rise to 643 million
by 2030. Diabetes mellitus type 2(DM2) is the most common type accounting almost 90% of
cases of DM. Diabetes mellitus clinically presents with polyuria, polydipsia, polyphagia,
paraesthesia. It can be correlated to Vimshati Prameha.
Objectives: To evaluate the combined effect of Lodhradi Kashaya and Navaka guggulu in the
management of Type 2 diabetes mellitus.
Methods: Among 34 registered subjects, 30 of them completed the course of treatment. They
were administered with Lodhradi Kashaya orally 25ml twice daily before food and Navaka
Guggulu 500mg tab twice daily after food for a period of 30 days. Blood glucose test was done
on 0th and 31st from the day of study initiation. For Statistical analysis subjective parameterswere assessed by Wilcoxson sign rank test and objective parameters were assessed by Paired
sample T Test.
Results: There was statistically significant improvement was observed in the signs and
symptoms of Madhumeha with blood glucose levels. (p<0.05)
Keywords: Diabetes Mellitus; Madhumeha; Lodhradi Kashaya, Navaka Guggulu Publication date: 01/03/2026 https://ijbpas.com/pdf/2026/March/MS_IJBPAS_2026_9945.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2026/15.3.9945