ABSTRACT

Since the beginning of time, people have utilized medicinal herbs to heal various ailments. People all across the world are impacted by the common problem of cancer. Research into new drugs to combat cancer is still underway, although the use of natural chemicals derived from plants in cancer chemotherapy has increased significantly in recent years. Andrographis paniculata (Brum. F) Nees is a well-known plant that has been studied as a possible cancer treatment in traditional Chinese and Indian medicine. Owing to these characteristics, A. paniculata is a viable choice for a plant-based anticancer drug. A. paniculata has a variety of pharmacological actions. This overview includes comprehensive information on the primary phytochemicals, their historical applications, pharmacology, and the purifying procedure used to extract them from A. paniculata. Its main active phytochemical, andrographolide, has been shown to have significant anticancer effects. These characteristics of A. paniculata make it a strong contender for a potential anticancer medication produced from plants. Medicinal plants have been used to treat illnesses since the prehistoric era. Cancer is a widespread issue that affects people all around the world. Recent years have seen a significant increase in the use of plant- derived natural compounds in cancer chemotherapy, and research into novel cancer-fighting medications is still ongoing. Researchers are looking into the highly known plant Andrographis paniculata (Brum. F) Neesin the context of traditional Chinese and Indian medicine as a potential cancer therapy. Due to these qualities, A. paniculata is a promising option for an anticancer medication generated from plants. The pharmacological effects of A. paniculata are multifaceted. In-depth details about the main phytochemicals, historical uses, pharmacology, and purification process of phytochemicals from A. paniculata are provided in this overview. There have been notable anticancer effects demonstrated by its primary active phytochemical, andrographolide. These qualities of A. paniculata make it a potent candidate as a prospective plant derived anticancer drug. Keywords: Medicinal plants; Phytochemicals; Andrographis paniculata; Anti-cancer; Andrographolide; Immunomodulatory
Publication date: 01/03/2026

https://ijbpas.com/pdf/2026/March/MS_IJBPAS_2026_9937.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.3.9937