ABSTRACT

Nanocochleates have emerged as a novel and promising approach in pharmaceuticals, offering unique advantages for drug delivery and therapy. Nanocochleates can encapsulate a variety of drugs, protecting them from degradation. A chelating agent can be designed to release the medication in a regulated way, which results in maintaining therapeutic levels in the body and reduction in side effects The small size of nanocochleates enables them to penetrate biological barriers more effectively, such as BBB, improving the bioavailability of drugs. In recent years, nanocochleates have gained attention for their potential applications in various disease treatments, including cancer, cardiovascular diseases, and infectious diseases. Their ability to deliver drugs to specific cells or tissues while minimizing systemic exposure holds great promise for personalized medicine. This review aims to provide an overview of nanocochleates, in the field of pharmaceutical sciences; we seek to clarify the possibility of using nanocochleates as a ground-breaking drug delivery mechanism. Keywords: Nanocochleates, drug delivery, chelating agent, targeted therapy, bioavailability
Publication date: 01/03/2026

https://ijbpas.com/pdf/2026/March/MS_IJBPAS_2026_9929.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.3.9929