ABSTRACT

Pyelonephritis is a severe bacterial infection of kidney parenchyma, often leading to kidney scarring, and is potentially life-threatening. Objective: The study was aimed at assessing the clinical profile, prognostic factors, and the 6-month outcome of patients with pyelonephritis. Methodology: This observational study involved qualitative and quantitative approaches to analyze various factors. The qualitative section includes those related to the antibiotics prescribed, symptoms, risk factors, and other demographic details, among which the latter two were approached quantitatively. Results: Ten patients who were randomly selected were involved in the study. The mean Age of the study group was 52.0 ± 8.628 years. Out of 10 subjects, 50% were males and 50% were females. Most of the subjects with Pyelonephritis suffered from symptoms like Pain (90%), pyrexia (80%), and Dysuria (70%). In our study, we had 20% subjects with Shock, 70% with Sepsis, and 20% with Disseminated Intravascular Coagulation. 10/10 cases had Type II Diabetes Mellitus. Four cases had unilateral involvement and six had bilateral involvement. Candida was the most common organism cultured (30%) followed by E. coli (20%). Eight cases Underwent DJ stent and one case had percutaneous nephrostomy. One subject with Advanced Disease expired. Antibiotics are irreplaceable drugs in the management of Pyelonephritis. All the patients were treated with IV Antibiotics and 8 Out of 10 subjects underwent surgical interventions. Conclusion: The disease should be suspected andinvestigated in both males and sick females with diabetes, with early recognition and appropriate management through medical and surgical therapies being crucial. Keywords: Pyelonephritis, Chronic Kidney Disease, IV Antibiotics, Uncontrolled Diabetes Mellitus, Unilateral and Bilateral involvement, E. coli and Candida species
Publication date: 01/02/2026

https://ijbpas.com/pdf/2026/February/MS_IJBPAS_2026_9836.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2026/15.2.9836