BENIGN PROSTATIC HYPERPLASIA: FROM ETIOLOGY TO TREATMENT – A PATHOPHYSIOLOGICAL PERSPECTIVE Authors: Hemasruthi K , JASMITHA M, JYOTHIPRIYA N, KARUNAKARAN K AND YAIDIKAR L*
ABSTRACT
Benign Prostatic Hyperplasia (BPH) is one of the most prevalent medical conditions
affecting the geriatric male population. The non-malignant enlargement of the prostate gland can
lead to a range of clinical symptoms, including difficulty in voiding, urinary retention, and
increased urinary frequency. The severity of symptoms often varies based on the degree of
prostate enlargement. The International Prostate Symptom Score (IPSS) remains the gold
standard for initial clinical assessment of BPH. However, recent advancements have introduced a
variety of new diagnostic tools that enhance understanding and precision in diagnosing prostate
hyperplasia. Over the past few years, BPH management has evolved significantly, with both
medical and surgical interventions aimed at improving the patient's quality of life and reducing
disease burden. Tailored pharmacological treatments, including alpha-blockers and 5-alpha-
reductase inhibitors, along with minimally invasive surgical techniques, provide effective options
to manage this condition, ultimately alleviating symptoms and improving long-term outcomes.
This review highlights the importance of early diagnosis and personalized treatment approaches
to effectively manage BPH and improve patient outcomes.
Keywords: Benign Prostatic Hyperplasia, Geriatric, International Prostatic Symptom Score Publication date: 01/02/2026 https://ijbpas.com/pdf/2026/February/MS_IJBPAS_2026_9818.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2026/15.2.9818