COMPREHENSIVE INSIGHTS FROM BIOSYNTHESIS TO TOXICOLOGY ON ?-ASARONE
Authors: Parmar U , DODIYA T* AND PRAJAPATI D

ABSTRACT
?-asarone is essentially isolated from the “Acorus species” and “Guatteria gaumeri Greenman”. ?- asarone is an extensively studied phytochemical. ?-asarone has significant pharmacological action reported by preclinical studies. The goal of the thorough review is to examine every piece of knowledge about ?-asarone's Isolation, biosynthesis, analytical techniques, and pharmacological activities. The review delves extensively into the stages that plants' enzymes take to synthesize ?-asarone. It can be biosynthesised via the Shikimate Pathway. Ultrasonic-assisted extraction, Chromatotron method, Soxhlet extraction, and other methods can be employed to extract and isolate ?-asarone from different plant parts and other medicinal products. Furthermore, the review addresses the identification and characterization of ?-asarone through a range of analytical methods, including GC-MS, HPLC, HPTLC, and others. The ?-asarone could be evaluated quantitatively and qualitatively using these methods. The compound has characteristics that include neuroprotective, anti-depressant, anti-Alzheimer, and genotoxic, which are useful in pharmacology and toxicology. To improve understanding of biological activities, ?-asarone isolation, and other subjects, a wealth of new information is included. establishing the most of each aspect for upcoming investigations will be greatly aided by this. Keywords: ?-asarone, Sweet Flag, ?-asarone extraction, Analytical characterization
Publication date: 01/01/2026
    https://ijbpas.com/pdf/2026/January/MS_IJBPAS_2026_9792.pdf
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https://doi.org/10.31032/IJBPAS/2026/15.1.9792