ABSTRACT

Back ground: Drug Utilization Review (DUR) is a planned and continuing process of reviewing drug prescribing, dispensing, and use to ensure optimal therapeutic outcomes. It is a quality improvement method that tries to encourage medication adherence while reducing adverse events, wasteful healthcare costs, and drug-related complications. Aim: The main of study is to determine drug utilization review on patients receiving metformin drug used in the treatment of type 2 DM. Method: It is retrospective study conducted for a period of 6 months in Gandhi Hospital, Secunderabad, Telangana, India. Total number of 140 patients who meets the study criteria is included in the study. The required data has been collected from case sheets, and medical records by using a suitable patient profile form, and obtained data will be evaluated statistically. Results: In this study, type 2 DM is more prevalent in males than females. Type 2 DM is more effectively cured when additional anti-diabetic drugs used along with metformin one compared to metformin alone used in the treatment. Management of type 2 DM with the medication metformin along with the combination and a diabetic drug with the timely and suitable approach with proper pharmaceutical care may lower the incidence. Significant difference was found in the GRBS and HbA1c levels in the patients who have been receiving metformin in combination with other anti-diabetic drugs (insulin or sulphonylureas) when compared to metformin alone used. Conclusion: It was found that type 2 DM is more prevalent in patients with hypertension 69% followed by CVS disease 20% as comorbid condition. Key words: Drug utilization review, diabetes mellitus, cardiovascular diseases, metformin, combinational therapy
Publication date: 01/01/2026

https://ijbpas.com/pdf/2026/January/MS_IJBPAS_2026_9721.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.1.9721