Background: Ghrita is one of the Ayurvedic drugs that contain ghee as the base to dissolve or extract or
hold the active therapeutic principles from the ingredients. Gandharyadi Ghrita is a medicated ghee
formulation, comprises of Gandhari (Fagonia cretica), Jatamamsi (Nardostachys jatamansi) and Go-
Ghrita (cow’s ghee). In Vaidya sara sangraha,Uttara Khanda Ekadasha prakarana ,it is mentioned that
administration of Gandharyadi ghrita nasya i.e., administered in the form of nasal drops cures
Ardhavabhedaka (Migraine ). In this study, an attempt has been made to standardize the physico-chemical
parameters for GG using modern tools. The aim of this study is to develop the pharmaceutical standards of
GG and to establish the analytical parameters of GG.
Material and Methods: Ghrita is prepared in the GMP-certified KLE Ayurveda Pharmacy, Belgaum,
Karnataka, India as per classical method. samples of GG were subjected to the analysis of organoleptic
characters and physicochemical parameters such as refractive index, moisture content, acid value, iodine
value, saponification value, rancidity value, microbial load, according to the Ayurvedic Pharmacopeia of
India, in Ayush-Approved ASU Drug Testing Laboratory, KAHER’s Shri B.M. Kankanwadi Ayurveda
Mahavidyalaya, Shahpur, Belgaum, Karnataka, India.
Result and Conclusion: Standardization tests done on Gandharyadi Ghrita are useful in authentication
and ensuring the quality of the same.
Keywords: Gandharyadi ghrita, analytical tests, physico-chemical, standardization
Publication date: 01/01/2026
https://ijbpas.com/pdf/2026/January/MS_IJBPAS_2026_9715.pdf
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https://doi.org/10.31032/IJBPAS/2026/15.1.9715
