Introduction: Non-Alcoholic Steatohepatitis (NASH) is a severe form of Non-Alcoholic Fatty Liver
Disease (NAFLD) characterized by liver inflammation, cell injury, and progressive fibrosis. The
condition poses a significant risk for advanced liver diseases including cirrhosis and hepatocellular
carcinoma. Despite advancements in understanding, treatment options remain limited. Ayurveda, with
its holistic approach, offers potential adjunctive strategies.
Methods: This review integrates current knowledge on NASH, including its epidemiology, pathology,
and conventional management approaches. It also explores Ayurvedic concepts relevant to liver health,
including diet, detoxification, and therapeutic herbs. A comparative analysis of Ayurvedic practices and
conventional treatments is presented.
Results: NASH is prevalent in adults aged 35-55, with significant variations in prevalence across
populations. Key diagnostic methods include liver imaging, serology, and biopsy. Conventional
treatments focus on lifestyle changes, weight management, and medications like vitamin E and
ursodeoxycholic acid. Ayurveda offers complementary approaches such as Panchakarma, dietarymodifications, and specific herbal formulations. Evidence suggests that Ayurvedic treatments can
enhance liver function, reduce inflammation, and improve metabolic health.
Discussion: While conventional treatments address symptoms and progression, Ayurvedic practices
provide additional benefits through detoxification and metabolic regulation. Ayurvedic formulations
like Arogya Vardhini Vati and Patolakaturohinyadi Kashaya show promise in managing NASH,
particularly by modulating lipid metabolism and inflammation. However, more rigorous clinical trials
are needed to validate these findings.
Conclusion: Integrating Ayurvedic therapies with conventional treatments may offer a holistic
approach to managing NASH. Further research is essential to establish the efficacy and safety of
Ayurvedic interventions, potentially enhancing treatment outcomes and patient quality of life.
Keywords: NASH, Liver disorders, Panchakarma, Pathya-Apathya, Yoga
Publication date: 01/12/2025
https://ijbpas.com/pdf/2025/December/MS_IJBPAS_2025_9673.pdf
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https://doi.org/10.31032/IJBPAS/2025/14.12.9673
