Adhatoda vasica means untouched by goats is derived from the fact of animals such as
goats avoid eating this plant owing to its intense bitterness. This plant is highly recognised in
traditional medical systems. The study focused on pharmacological activities of vasicine from
Adhatoda vasica namely anti-bacterial activity, antitubercular activity, insecticidal activity,
muscle stimulant activity, allelopathic activity, anti pyorrhoeal activity, anti-ulcer activity,
allopathic activity, sucrose inhibitory activity, anti- inflammatory activity, abortifacient
activity, antioxidant activity, anti-alzheimer’s activity, HIV-protease inhibitor activity,
antifungal activity,WBC increasing activity, H1N1 flu prevention activity, anti-allergy activity,
hepatoprotective activity, anti-diabetes activity, in-vitro antiurolithiatic activity, cholagogue
activity, anti-asthmatic activity, anthelmintic activity, anticestodal activity, wound healing,
digestion, radio modulation, anti-mutagenic activity, antiviral activity, anti-malarial activity,
antimicrobial activity, antispasmodic activity, anticancer activity, thrombolytic activity and
renal protective activities respectively. This plant is a sedative, expectorant, antispasmodic, and
anthelmintic that helps to cure colds, coughs, whooping cough, chronic bronchitis, and asthma.
Vasicine's anti-inflammatory, antibacterial, and antioxidant activities have also been studied,
pointing to a larger therapeutic potential beyond respiratory health. The plant includes alkaloids
such as vasicine, vasicinone, deoxyvasicine, vasicol, adhatodinine, and vasicinol.
Keywords: Vasicine, Chronic bronchitis, Pharmacological, Expectorant
Publication date: 01/12/2025
https://ijbpas.com/pdf/2025/December/MS_IJBPAS_2025_9656.pdf
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https://doi.org/10.31032/IJBPAS/2025/14.12.9656
