ABSTRACT

The research work investigates the synthesis, spectroscopic characterization, and in vitro antibacterial activity of a Co(II) transition metal complex. The metal complex was synthesized by reacting the respective pyrazolone-based ligand. The synthesized ligand was characterized by ¹H NMR, mass, IR, UV, and elemental analysis, while the respective complex was characterized by IR, UV, and elemental analysis. The results confirmed that the synthesized Co(II) metal complex has promising antibacterial activity against Gram-positive (Bacillus megaterium) and Gram-negative (E. coli) microorganisms, which makes it a potential candidate for the development of a new antibacterial agent. Keywords: Cobalt complex, Schiff base, Phenyl hydrazine, Pyrazolone and antibacterial activity
Publication date: 01/12/2025

https://ijbpas.com/pdf/2025/December/MS_IJBPAS_2025_9654.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2025/14.12.9654