ABSTRACT

Traditional medicinal herbs are widely used globally and have increasingly captured the interest of scientific and pharmaceutical communities. Recent research highlights their potential therapeutic benefits, particularly their ability to combat drug-resistant infections with their strong antibacterial properties. This has spurred investigations into the active components and processes of these plants, revealing promising avenues for new antimicrobial medicines. With the rise of novel infectious diseases and antibiotic resistance, exploring plants as sources of diverse and potent chemical compounds is critically important. In Ayurveda and other traditional medicine systems, Withania somnifera is a significant medicinal herb. Current research shows that the ethanolic extract of Withania somnifera is highly efficient against fungal cultures of A. niger, Candida albicans, Trichoderma asperellum, Candida tropicalis, and Candida parapsilosis. Various concentrations of Withania somnifera 's ethanolic extracts (20, 40, 60, 80, and 100 microliters) were applied to these fungal cultures. It was discovered that the 100 ????l concentration (50 mg/ml) worked best against the fungus cultures. The maximum inhibition zone (measured in millimeters) was found against A. niger (21 mm), with T. asperellum (17.5 ± 0.5), C. tropicalis (17 mm), C. parapsilosis (15.5 mm ± 0.70711), and C. albicans (14.5 mm± 0.70710678) following closely behind. Keywords: Withania somnifera , A. niger, Candida albicans, Trichoderma asperellum, Candida tropicalis, and Candida parapsilosis
Publication date: 01/11/2025

https://ijbpas.com/pdf/2025/November/MS_IJBPAS_2025_9552.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.11.9552