ABSTRACT

Urinary tract infections (UTIs) are a major public health concern throughout the world, and they are frequently associated with the occurrence of urinary stones, specifically struvite stones. The present study concentrated on an economical and environmentally friendly method for producing zinc nanoparticles utilizing Mellingtonia hortensis flower extract as a reducing and capping agent. We evaluated the potential of these nanoparticles as Antioxidant, Antiurolithiatic and Antimicrobial activity. These nanoparticles were characterized by UV-Visible spectroscopy and it shown the absorption band at 256nm. According to FT-IR spectroscopic investigations, phytoconstituents have a major role in the reduction and capping of zinc nanoparticles, Mellingtonia hortensis mediated zinc nanoparticles were crystallized and had a spherical shape, in XRD and SEM. The EDX analysis showed the elemental composition and the amount of zinc nanoparticles. The zinc nanoparticles mediated by Millingtonia hortensis were found to have an inhibitory efficiency of 88.3%. This results showing that they were an effective inhibitor for destruvite crystals. The maximum zone of inhibition was observed against at a concentration 100?g/ml. In conclusion, the synthesized Zinc Nanoparticles using Millingtonia hortensis shown most promising Antioxidant, Antiurolithiatic and Antimicrobial activities against struvite urinary stones and UTI Infection Keywords: Millingtonia hortensis, Zinc nanoparticles, Antiurolithiatic activity, FTIR, EDAX, Phytoconstituents
Publication date: 01/10/2025

https://ijbpas.com/pdf/2025/October/MS_IJBPAS_2025_9491.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.10.9491