TO ASSESS THE EFFECTIVENESS OF ANTIHYPERTENSIVE AGENTS IN CORONARY ARTERY DISEASE PATIENTS
Authors: Jani K , SHAH A, JAIN S, KAPADIA N, PARIHAR SS, CHAUDHARY A AND PATEL V

ABSTRACT
Introduction: Coronary artery disease (CAD) is significantly influenced by hypertension in all age and gender categories. High blood pressure is treated using antihypertensive drugs, some of which aid in the body’s elimination of extra fluid and salt. Beta-blockers, statins, diuretics, ACE inhibitors, and blockers of angiotensin receptors should all be used in suitable therapy. The study's purpose was to determine which antihypertensives are used most frequently, while simultaneously monitoring patient heart rate and ECG changes, as well as the efficacy of antihypertensive drugs in patients with coronary artery disease. Materials and Methods: It is a prospective observational research conducted at Apollo Hospital. Patients were identified using exclusion and inclusion criteria. The effectiveness of antihypertensive medicine provided to CAD patients was studied. Results: The study included 260 patients, with 190 (73%) males and 70 (27%) females. The Heart rate of the patients varied by 2.809%, indicating that the drug is having the desired effect and that the person has undergone noticeable alterations. The study indicates that statins, beta-blockers, and aspirin are administered to the patient in the highest quantities. The most often given antihypertensive medicinecombinations comprise, beta blocker, statin, and diuretics. They have been considered to be an essential aspect of treatment for those with coronary artery disease. Conclusion: In the management of people with CAD, selecting the right drug combination and taking antihypertensive drugs correctly can be critical. Keywords: Antihypertensive, cardio protective, ECG-abnormality, Efficacy, Heart rate, Observational study
Publication date: 01/09/2025
    https://ijbpas.com/pdf/2025/September/MS_IJBPAS_2025_9419.pdf
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https://doi.org/10.31032/IJBPAS/2025/14.9.9419