TO ASSESS THE EFFECTIVENESS OF ANTIHYPERTENSIVE AGENTS IN CORONARY ARTERY DISEASE PATIENTS Authors: Jani K , SHAH A, JAIN S, KAPADIA N, PARIHAR SS, CHAUDHARY A AND PATEL V
ABSTRACT
Introduction: Coronary artery disease (CAD) is significantly influenced by hypertension in all age and
gender categories. High blood pressure is treated using antihypertensive drugs, some of which aid in
the body’s elimination of extra fluid and salt. Beta-blockers, statins, diuretics, ACE inhibitors, and
blockers of angiotensin receptors should all be used in suitable therapy. The study's purpose was to
determine which antihypertensives are used most frequently, while simultaneously monitoring patient
heart rate and ECG changes, as well as the efficacy of antihypertensive drugs in patients with coronary
artery disease.
Materials and Methods: It is a prospective observational research conducted at Apollo Hospital.
Patients were identified using exclusion and inclusion criteria. The effectiveness of antihypertensive
medicine provided to CAD patients was studied.
Results: The study included 260 patients, with 190 (73%) males and 70 (27%) females. The Heart rate
of the patients varied by 2.809%, indicating that the drug is having the desired effect and that the person
has undergone noticeable alterations. The study indicates that statins, beta-blockers, and aspirin are
administered to the patient in the highest quantities. The most often given antihypertensive medicinecombinations comprise, beta blocker, statin, and diuretics. They have been considered to be an essential
aspect of treatment for those with coronary artery disease.
Conclusion: In the management of people with CAD, selecting the right drug combination and taking
antihypertensive drugs correctly can be critical.
Keywords: Antihypertensive, cardio protective, ECG-abnormality, Efficacy, Heart rate,
Observational study Publication date: 01/09/2025 https://ijbpas.com/pdf/2025/September/MS_IJBPAS_2025_9419.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.9.9419