DEVELOPMENT OF UV-SPECTROPHOTOMETRIC METHOD FOR ELETRIPTAN IN PURE AND DOSAGE FORM Authors: Sridevi Ranjitha K , DILIP KUMAR R, SAILAJA U, BHAVANA R, VARAPRASADARAO K, RAJESH BABU KB*
ABSTRACT
This study primarily focuses on developing a novel UV method for the assay of Eletriptan in both
pure form and pharmaceutical dosage forms. The process involves preparing standard and working
solutions of Eletriptan, followed by the analysis of different concentrations of the working
solution. The established method is then subjected to validation as per ICH guidelines. The results
indicate that the developed method is sensitive and accurate, particularly within the concentration
range of 10-60 ?g/ml. The correlation coefficient (R2) was determined to be 0.999. Notably, there
was no interference observed with the excipients present in the formulation. The proposed method
holds potential for the analysis of Eletriptan in bulk and formulation, making it suitable for routine
analysis
Keywords: Ultraviolet Spectroscopy, validation, Eletriptan, method development, assay Publication date: 01/09/2025 https://ijbpas.com/pdf/2025/September/MS_IJBPAS_2025_8845.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.9.8845