ABSTRACT

Medicinal plants have curative properties due to the presence of various complex chemical substances of different composition, which are found as secondary plant metabolites in one or more parts of these plants. Sapindus trifoliatus, commonly known as soap nut, has been traditionally utilized for various medicinal purposes. This study investigates the in vitro anti- bacterial and anti-helminthic activities of Sapindus trifoliatus seed extract. The extraction process was carried out using methanol solvent. The anti-bacterial potential of the extract was evaluated against a panel of pathogenic microorganisms, bacteria and using standard microbiological assays. The findings reveal significant inhibitory effects, suggesting a promising role for Sapindus trifoliatus seed extract in combating microbial infections. Furthermore, the extract exhibited noteworthy anti-helminthic activity against common parasitic worms, as evidenced by in vitro assays. The study elucidates the possible mechanisms underlying the observed activities, shedding light on the phytochemical composition responsible for the extract's efficacy. In conclusion, Sapindus trifoliatus seed extract emerges as a potential source of natural compounds with anti-bacterial and anti-helminthic properties. This research contributes valuable insights into the therapeutic applications of Sapindustrifoliatus, paving the way for further exploration and development of novel pharmacological agents derived from this plant species. Keywords: Sapindus trifoliatus, anti-bacterial activity, anthelmintic activity, Pheretima posthuma
Publication date: 01/07/2025

https://ijbpas.com/pdf/2025/July/MS_IJBPAS_2025_9254.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.7.9254