AN OBSERVATIONAL COMPARISON STUDY OF CORTICOSTEROIDS AND BRONCHODILATORS IN PNEUMONIA AND ACUTE BRONCHITIS IN PEDIATRIC GROUP Authors: Paul M , DAS K, MOZHI K AND SAHITHYA L
ABSTRACT
Background: Pneumonia and acute bronchitis are the major life threatening condition in
children. Especially in India, these conditions are very common and around 4 lakhs children
aged below five years die every year from multiple diseases cause by acute respiratory
infection.
Purpose: To examine the prescription behaviour of glucocorticoids and bronchodilators in
pneumonia and acute bronchitis in children.
Methods: The approval of the human ethics committee was obtained from Aditya Bangalore
Institute of Pharmacy Education and Research, Bangalore. Enrolled were the patients who met
the study's eligibility requirements. The patient's demographic was entered. Data on the
patient's demographics, clinical condition, and medications was gathered and entered into
specially created documentation forms. Descriptive statistics were used to evaluate the
obtained data.
Results: There were 101 children involved in the study, ranging in age from 1 year to 15 years.
It includes males and females equally. Most of the prescriptions contained Bronchodilators and
antibiotics. Among them, the bronchodilators group of drugs Levo salbutamol nebulizer
(35.145%), in the corticosteroid group, prednisolone syrup (16.25%), and in antibiotics group,cephalosporins (68%) were prescribed mostly. syrup formulations containing prednisolone and
inhaler formulation bronchodilators were used widely.
Conclusion: As a first-line choice bronchodilator Lev. salbutamol is used in treating
pneumonia and acute bronchitis. The first line choice of corticosteroids is prednisolone syrup.
Cephalosporins are the antibiotics that are used in a wide range for both diseases whereas all
bronchodilators were given in nebulization form and corticosteroids were given in oral route.
All the prescribed drugs were within the FDA-recommended dose range in children.
Keywords: Acute bronchitis, antibiotics, bronchodilators, corticosteroids, pneumonia Publication date: 01/06/2025 https://ijbpas.com/pdf/2025/June/MS_IJBPAS_2025_9147.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.6.9147