ABSTRACT

This study undertakes a meticulous examination of past endeavors on solid dispersions using the Quality by Design (QbD) approach, offering in-depth insights into their types and methods of preparation. Through a comprehensive review of peer-reviewed literature, the research elucidates the effectiveness of solid dispersion techniques in addressing the inherent solubility limitations of poorly soluble drugs. Noteworthy among these findings is the emergence of the QbD approach as a transformative methodology in experimental design, providing a structured framework for the systematic optimization of drug formulations. By synthesizing past research and illuminating key insights, this review aims to serve as an invaluable resource for aspiring researchers, equipping them with a nuanced understanding of solid dispersions by QbD and facilitating expedited access to pertinent information for future investigations in this dynamic field. Keywords: Bioavailability, Quality by design, Release, Solid dispersions, Solubility
Publication date: 01/06/2025

https://ijbpas.com/pdf/2025/June/MS_IJBPAS_2025_9103.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.6.9103