ABSTRACT

Study objective: CLD is a major issue on a global scale and it affects people of all ages, genders, and ethnicities and is the root of a high number of medical consultations, hospital admissions, medical costs, morbidity and mortality. The aim is to study the prescribing pattern of drugs used in the treatment of CLD. The objectives are to assess the pattern of clinical features, risk factors, co-morbidities and complications associated with CLD. To assess the stages of cirrhosis and study the mortality rate of the patient using MELD score. Methodology: A prospective observational study was conducted in a tertiary care hospital for a duration of 6 months. Result: Among 68 participants, the majority of them were in the age group of 56- 65 (35.29%) and 53 (78%) of the study population were predominantly male. Diabetes (45.8%) was observed to be the major risk factor followed by alcohol (38.6%) and NASH (10.8%). The most observed clinical feature was abdominal distension (20/42%). Anemia (26%) and diabetes mellitus (22%) were the most commonlyobserved comorbidities. Portal hypertension (30.32%) is the most common complication seen, followed by ascites and esophageal varices. The majority of participants belonged to Child-Pugh Class C and a MELD Na Score ranging 20-29 (50%). On evaluation, the most frequently prescribed drugs were gastrointestinal agents (38.49%) followed by dietary supplements (19.54%). Conclusion: Chronic Liver Disease is increasingly becoming more prevalent, and part of this rise can be attributed to improved detection of risk factors, clinical features, complications and comorbidities. In-depth clinical care plans must include strategies for preventing, diagnosing, treating, and palliating these problems. Future interventions to raise public awareness of CLD should be taken promptly. Keywords: Chronic Liver Disease (CLD); Liver cirrhosis; Risk factors; Model for end stage liver disease (MELD); Child- Pugh Classification
Publication date: 01/06/2025

https://ijbpas.com/pdf/2025/June/MS_IJBPAS_2025_9100.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.6.9100