CONCEPTUAL UNDERSTANDING OF MYASTHENIA GRAVIS ON THE BASIS OF VYANVAYU AND OTHER VYADHI GHATAK Authors: Makwana K And Bhoir M*
ABSTRACT
In Myasthenia gravis is a disease, where AChRs in the neuromuscular junction are destroyed
by immune bodies which develop due to an autoimmune disease [1]. Treatment is use
anticholine esterase drugs and immunosuppressive drugs (to suppress the immune bodies
which destroy the AChRs). Myasthenia gravis has prevalence as high 200 in 100,000. It affects
individuals in all age groups, but peak incidences occur in women in their twenties and thirties
and in men in their fifties and sixties. Overall, women are affected more frequently than men,
in a ratio of 3:2.
In MG, the fundamental defect is a decrease in the number of available AChRs at the
postsynaptic muscle membrane. It presents with fluctuating skeletal muscle weakness and
fatigue most commonly affecting the ocular muscles, although any muscle may be affected.
Ayurvedic therapies can give much more promising results. Comparison between myasthenia
gravis and diseases explained in Ayurveda is difficult and exact correlation is not possible. But
based on critical understanding of prakrut karma of vyan vayu and its vikrut karma and also
included other vyadhighataka, a probable diagnosis can be made and treated accordingly.In this article, attempt is made to understand the pathogenesis of myasthenia gravis by
considering the concepts vitiated Dosha vyanvayu, Dushya- Aama, Agnimandya, and
Srotovaigunya. For any disease pathology to begin, all components must be present.
Pathogenesis of any disease will not occur without these elements.
Keywords: Myasthenia Gravis, Vyanvayu, Vyadhi Ghatak Publication date: 01/06/2025 https://ijbpas.com/pdf/2025/June/MS_IJBPAS_2025_9073.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.6.9073