ABSTRACT

Now-a-days there is increasing demands of improved excipients functionality due to limitations of existing excipients failing to comply with all the functionalities of an ideal excipient. Co-processing represents a simple, efficient and economical approach for the development of high-functionality excipients. Co-processed excipient has received much more attention in the formulation development of various dosage forms, especially for tablet preparation by direct compression method. Tablet manufacturing has been changed by the introduction of the direct?compression process and high?speed machines. These two developments have increased the demands on the functionality of excipients in terms of flow and compression properties. The objective of this review is to discuss the emergence of co- processed excipients as a current and future trend of excipient technology in pharmaceutical companies. Co- processing is a novel concept of combining two or more excipients that possess specific advantages that cannot be achieved using a physical admixture of the same combination of excipients. This review article discusses the recent development in excipient technology and the approaches involved in development of such excipients. Keywords: Co-processed excipient, Excipient technology, Direct?compression, Tablets
Publication date: 01/06/2025

https://ijbpas.com/pdf/2025/June/MS_IJBPAS_2025_9070.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.6.9070