ABSTRACT

This review examined naturally occurring humic compounds, such as fulvic acid, humus, and humic acid, which vary in composition depending on where they are found and the extraction method employed. They have various groups in their molecular structures, such as phenols and carboxylic acids. In this setting, humic substances—such as inclusion complexes like cyclodextrin with hydrophobic drugs—have emerged as essential excipients for the future. It is subsequently utilized in medication delivery systems, medicines, and nutraceuticals. Despite the fact that humic acid has several therapeutic uses, not much is known about its worldwide market, solubility, pH, etc. The potential of pharmaceutical excipients, which are based on the idea that they can improve the solubility and bioavailability of biopharmaceutical medications, is also examined in this review. Keywords: Humic acid, Cyclodextrin, Carboxylic acids, enhance solubility
Publication date: 01/06/2025

https://ijbpas.com/pdf/2025/June/MS_IJBPAS_2025_9014.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.6.9014