ABSTRACT

Class of microbes that invades and causes inflammation of various tissues including dermis, subcutaneous tissues and epidermis tissues are the main reason of infections of skin. SSTIs can be categorized as complicated, non-complicated, purulent, and non-purulent on the evidence of clinical symptoms and severity. S. aureus is the of the leading cause of skin infections. One of the major causes of Hospital acquires and Community acquired skin infections is MRSA due to its resistance to lactam antibiotics. Establishment of antimicrobial activity of different bacterial isolates obtained from skin and pus swabs. 173 isolates were analyzed for bacterial group and antimicrobial activity was determined. Amplification of mecA gene was performed by Polymerase chain reaction. Out of 173 samples, 37 were MRSA isolates of which 29 (78.3%) were resistant to Amikacin and 33(89.1%) were sensitive to Linezolid. MRSA has become an emerging pathogen in skin infections from mild to severe due to its resistance to beta-lactam antibiotics. The study demonstrates the distribution of different bacterial isolates in the infections of skin and soft tissues. S. aureus is a concern and immediate biosecurity measures are recommended to limit its spread within hospital settings. Keywords: Staphylococcus aureus, methicillin resistant. Skin and soft tissues
Publication date: 01/06/2025

https://ijbpas.com/pdf/2025/June/MS_IJBPAS_2025_86231.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.6.8623