ASSESSMENT OF RISK FACTORS AND ANTIBIOTIC SENSITIVITY PATTERN IN CATHETER-ASSOCIATED URINARY TRACT INFECTION (CAUTI) Authors: Malini S , JOSSY A, GEORGE AF, JIJI M, JOSHUA JM, MATHEWS SM AND VARGHESE S
ABSTRACT
Background: Catheter-associated urinary tract infections (CAUTI) are a serious healthcare-
associated infection. Many risk factors are associated with its incidence. The growing antibiotic
resistance amongst the uropathogen isolated from CAUTI making difficult for its management. In
our study we aimed to identify the agents causing CAUTI and their antibiotic sensitivity patterns
as well as to analyse the risk factors associated with CAUTI.
Methods: A Prospective Observational study was conducted in Department of General Medicine,
in Pushpagiri Medical College Hospital, Thiruvalla. The study was conducted in 81 CAUTI
patients for a period of six months. The study population included patients admitted with
complaints of CAUTI who satisfied inclusion and exclusion criteria.
Results: On analysing the patient and catheter related risk factors, age greater than 50 years
(24.52%), prolonged duration of catheterisation (23.25%) and diabetes (16.56%) were found to be
the significant risk factors associated with CAUTI. The most prevalent uropathogen identified inour study was Klebsiella pneumonia (46.91%) followed by E.coli (29.63%). Very high
antimicrobial resistance was found in Klebsiella pneumonia and E.coli species in the present study.
There was significant improvement in the overall quality of life(p=0.000) after the implementation
of the education programme.
Conclusion: The study findings confirmed that most of the uropathogen isolated from CAUTI are
resistant to the commonly used antibiotics. This raises alarms to implement Antimicrobial
Stewardship programmes with strict adherence to antibiotic policy to reduce the spread of drug
resistant microbes which in turn can lower overall cost of health care.
Keywords: CAUTI, Risk factors, Uropathogen, Antibiotic resistance Publication date: 01/05/2025 https://ijbpas.com/pdf/2025/May/MS_IJBPAS_2025_9017.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.5.9017