ABSTRACT

Oral mucositis is arguably the most prevalent and crippling side effect of cancer treatments, especially chemotherapy and radiation. It can cause a number of issues, such as pain, nutritional deficiencies from not being able to eat, and an increased risk of infection from open sores in the mucosa. It can also be dose-limiting. The study's objective was to evaluate the effects of salaine and chlorhexidine on oral mucositis. Non-randomized comparative research design was used as the study's research method. A sample of sixty patients with oral mucositis who met the inclusion criteria was obtained using non-probabilistic judgmental sampling approaches. The WHO oral mucositis scale was used for both the pre- and post-test. Experiment I was told to rinse their mouth with chlorhexidine after the pre-test, while experimental group II was told to use saline mouthwash. In experimental group I pre test mean 2.86 (SD 0.8695) and the post test mean was 0.52 (SD 0.3642), the paired ‘t’ value was 5.8607. In experimental group II pre test mean 2.98 (SD 0.7532) and the post test mean was 0.89 (SD 0.4215), the paired ‘t’ value was 4.4071. Unpaired ‘t’ value 2.0058 which is significant at P< 0.05 level. The results showed that when it came to lowering the degree of oral mucositis in cancer patients, chlorhexidine outperformed saline. Chisquare analysis revealed that, with the exception of length of illness and frequency of mouth care, there was no significant correlation between the clinical and demographic characteristics of cancer patients with oral mucositis in experimental groups I and II. Key words: Chlorhexidine, Saline, Oral, Mucositis, Cancer, Patients
Publication date: 01/05/2025

https://ijbpas.com/pdf/2025/May/MS_IJBPAS_2025_8997.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.5.8997