DESIGN DEVELOPMENT AND EVALUATION OF NOVEL FORMULATION FOR WOUND HEALING ACTIVITY Authors: Yelmate AA , SATPUTE KL, EKLINGE SS AND SABNE AA
ABSTRACT
Wound is an anti-inflammatory condition associated with skin rashes, gunfire, flaming objects, surgery,
cutting, and piercing substances etc. Wound causes by disruption of skin tissue while it has internal or
external in origin. Both internal and external sources of wounds are possible. Internal wounds are typically
brought on by poor circulation, neuropathy, or a medical condition. Open or closed wounds caused by an
external force or trauma are known as wounds of external origin. There are many possible cure but they
associated with disadvantages in the allopathic medicines has need to develop the new formulations from
natural remedies with wound healing activity. Moringa oleifera, Annona squamosa, Tridax procumbens
found to be efficacious and anti-inflammatory drug with least side effects as compared to synthetic drugs
used in treatment of wound. Fundamental to wound research is identifying the basic mechanisms of healing
and then controlling these mechanisms to promote quicker healing or prevent undesirable outcomes like
infection or scarring. A complex biological process called wound healing occurs inflammation,
proliferation, remodeling, and hemostasis. With the aforementioned justification in mind, an effort was
undertaken to design and develop herbal nanogel and test it for anti-inflammatory properties. The
formulation was evaluated for its in vivo anti-inflammatory efficacy, pH, particle size, viscosity,
homogeneity, and consistency.
Keywords: Anti-inflammatory, Wound, Nanogel, Polyherbal Publication date: 01/05/2025 https://ijbpas.com/pdf/2025/May/MS_IJBPAS_2025_8963.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.5.8963