OVERCOMING DRUG RESISTANCE IN BREAST CANCER: NOVEL STRATEGIES AND THERAPEUTIC APPROACHES Authors: Batra K , SAHU P, SAHU D, GUPTA N, GUPTA A, SHARMA H AND SAHU GK*
ABSTRACT
Breast cancer remains a significant global health burden, driving ongoing efforts in research and
therapeutic development. This review paper explores promising avenues for future research and
therapeutic advancement in breast cancer. Immunotherapy emerges as a transformative approach,
with immune checkpoint inhibitors and CAR T-cell therapy offering new avenues for enhancing
anti-tumor immune responses. Precision medicine initiatives, guided by biomarker-driven therapy
selection and targeted therapy expansion, are revolutionizing treatment approaches and improving
patient outcomes. Novel drug delivery systems, including nanomedicine-based approaches and
liposomal formulations, show promise in optimizing drug delivery and overcoming resistance
mechanisms. Modulation of the tumor microenvironment and exploration of combination
therapies offer synergistic approaches to enhance treatment efficacy. By leveraging these
advancements and fostering collaborative efforts, we can drive progress in breast cancer research,
translate scientific discoveries into clinical practice, and ultimately improve outcomes for patients
worldwide.
Keywords: Breast Cancer, Novel drug delivery system, Nanotechnology Publication date: 01/04/2025 https://ijbpas.com/pdf/2025/April/MS_IJBPAS_2025_8948.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.4.8948