OVERCOMING DRUG RESISTANCE IN BREAST CANCER: NOVEL STRATEGIES AND THERAPEUTIC APPROACHES
Authors: Batra K , SAHU P, SAHU D, GUPTA N, GUPTA A, SHARMA H AND SAHU GK*

ABSTRACT
Breast cancer remains a significant global health burden, driving ongoing efforts in research and therapeutic development. This review paper explores promising avenues for future research and therapeutic advancement in breast cancer. Immunotherapy emerges as a transformative approach, with immune checkpoint inhibitors and CAR T-cell therapy offering new avenues for enhancing anti-tumor immune responses. Precision medicine initiatives, guided by biomarker-driven therapy selection and targeted therapy expansion, are revolutionizing treatment approaches and improving patient outcomes. Novel drug delivery systems, including nanomedicine-based approaches and liposomal formulations, show promise in optimizing drug delivery and overcoming resistance mechanisms. Modulation of the tumor microenvironment and exploration of combination therapies offer synergistic approaches to enhance treatment efficacy. By leveraging these advancements and fostering collaborative efforts, we can drive progress in breast cancer research, translate scientific discoveries into clinical practice, and ultimately improve outcomes for patients worldwide. Keywords: Breast Cancer, Novel drug delivery system, Nanotechnology
Publication date: 01/04/2025
    https://ijbpas.com/pdf/2025/April/MS_IJBPAS_2025_8948.pdf
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https://doi.org/10.31032/IJBPAS/2025/14.4.8948