ASSESSMENT OF ANGIOGENIC EFFECT OF SWARNA MAKSHIKA BHASMA: A CAM MODEL STUDY PROTOCOL
Authors: Suryawanshi N , GHAROTE A, TOMAR E AND KONDAR S

ABSTRACT
Background: Swarna Makshika Bhasma, a herbo-mineral compound is widely used in many diseases like Pandu, Kamala, Kushtha etc. It has specific properties like Pittashamana and Raktaprasadana. In the present study Swarna Makshika Bhasma will be prepared with a standardized method w.s.r. To Rasaratnasamuchchaya and its angiogenic effect will be tested with the Chick Chorioallantoic membrane (CAM) model. This study aims to investigate potential impact of Swarna Makshika Bhasma on angiogenesis and establish its effect on Raktadhatu using more reliable and cost-effective method like CAM. Objectives: 1. To prepare Swarna Makshika Bhasma 2. Physicochemical and Analytical study of Swarna Makshika Bhasma 3. To assess of effect of Swarna Makshika Bhasma on angiogenesis 4. To compare angiogenic potential of Swarna Makshika Bhasma with standard drug Progesterone Methodology: Classical and contemporary literature will be reviewed and the data will be collected. Swarna Makshika Shodhana with Matulunga swarasa and marana with Gandhaka (Sulphur) will be done. Analytical tests like classical Bhasma pariksha, physicochemical analysis and advance analysis like XRD and SEM-EDX will be done. Expected Results: The results based on pharmaceutical study, analytical study and experimental study will be observed and noted to define the conclusion. Keywords: Swarna Makshika; Angiogenic Potential; Chick Embryo; CAM model
Publication date: 01/04/2025
    https://ijbpas.com/pdf/2025/April/MS_IJBPAS_2025_88411.pdf
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https://doi.org/10.31032/IJBPAS/2025/14.4.8841