ASSESSMENT OF ANGIOGENIC EFFECT OF SWARNA MAKSHIKA BHASMA: A CAM MODEL STUDY PROTOCOL Authors: Suryawanshi N , GHAROTE A, TOMAR E AND KONDAR S
ABSTRACT
Background: Swarna Makshika Bhasma, a herbo-mineral compound is widely used in many diseases
like Pandu, Kamala, Kushtha etc. It has specific properties like Pittashamana and Raktaprasadana. In
the present study Swarna Makshika Bhasma will be prepared with a standardized method w.s.r. To
Rasaratnasamuchchaya and its angiogenic effect will be tested with the Chick Chorioallantoic
membrane (CAM) model. This study aims to investigate potential impact of Swarna Makshika Bhasma
on angiogenesis and establish its effect on Raktadhatu using more reliable and cost-effective method
like CAM.
Objectives: 1. To prepare Swarna Makshika Bhasma
2. Physicochemical and Analytical study of Swarna Makshika Bhasma
3. To assess of effect of Swarna Makshika Bhasma on angiogenesis
4. To compare angiogenic potential of Swarna Makshika Bhasma with standard drug Progesterone
Methodology: Classical and contemporary literature will be reviewed and the data will be collected.
Swarna Makshika Shodhana with Matulunga swarasa and marana with Gandhaka (Sulphur) will be
done. Analytical tests like classical Bhasma pariksha, physicochemical analysis and advance analysis
like XRD and SEM-EDX will be done.
Expected Results: The results based on pharmaceutical study, analytical study and experimental study
will be observed and noted to define the conclusion.
Keywords: Swarna Makshika; Angiogenic Potential; Chick Embryo; CAM model Publication date: 01/04/2025 https://ijbpas.com/pdf/2025/April/MS_IJBPAS_2025_88411.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.4.8841