ABSTRACT

This study aims to analyze a hydroalcoholic extract of Ananas comosus leaf for anthelmintic properties. It is frequently utilized in the Ayurvedic medical system to treat oxidative stress, joint discomfort, anti-inflammatory, enzyme inhibitory, and cytotoxic effects. It is also used as a folk remedy for these conditions. It has been demonstrated by science that the remaining plant portions have anthelmintic properties. We try to look into this activity because there are currently no scientific data on Ananas comosus leaves, despite the fact that the most significant activities such as glucose uptake, enzyme inhibitory action, and auxin transportation have already been demonstrated. Ananas comosus leaves were allowed to macerate to produce a hydroalcoholic extract, and several phytochemical analyses were carried out. An investigation into the anthelmintic activity was carried out using the limit test, main test, and comparative test. The ‘Tubifex tubifex worms' paralysis and death time were tracked, and the lowest dose concentration needed to kill every test a worm in 4 hours was computed. The usual medication was albendazole as suspension. Using a one-way ANNOVA and Dunnett's post-parametric test between the test group and the standard group data, the data is highly significant (P<0.01). Consequently, there may be an essential for Ananas comosus leaf hydroalcoholic extract as a natural anthelmintic. Keywords: Hydroalcoholic extract, Ananas comosus, Tubifex tubifex, paralysis and death time, albendazole, ANNOVA
Publication date: 15/03/2025

https://ijbpas.com/pdf/2025/March/MS_IJBPAS_2025_MARCH_SPCL_1042.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.3.1042