ABSTRACT

The present study evaluated the antioxidant and antibacterial activities and phytochemical investigation of aqueous extract of Rosa Damascena Mill. Stem. The antioxidant activity was evaluated by the DPPH assay method and antibacterial activity was determined by disc diffusion method. The aqueous extract showed high antioxidant activity (73.07%) and had antibacterial activity against both Gram-positive and Gram-negative bacteria. A higher inhibition zone was detected against Staphylococcus aureus -18mm, Pseudomonas aeruginosa-13mm, Bacillus subtilis-11mm, and Escherichia coli-9mm at 100?g/ml concentration. The minimum zone of inhibition was detected at 60?g/ml concentration. Preliminary phytochemical exploration indicated the presence of Alkaloids, Carbohydrates, Flavonoids, Saponins, Proteins, Starch, Free amino acids, Fixed oil and fat, and Steroids. The result indicated that the aqueous extract of R.Damascena mill stem possessed strong antibacterial and antioxidant properties and could be an important source of natural compounds for the development of a new drug. Keyword: Antioxidant, Antibacterial, Aqueous extract, Phytochemical, Rosa Damascena Mill.
Publication date: 15/03/2025

https://ijbpas.com/pdf/2025/March/MS_IJBPAS_2025_MARCH_SPCL_1013.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2025/14.3.1013