AMELIORATIVE EFFECT OF BEE POLLEN AND BEE PROPOLIS ON CATALASE ACTIVITY AGAINST ANTITUBERCULOSIS DRUGS RIFAMPICIN AND ISONIAZID IN SPRAGUE DAWLEY RATS
Authors: Bharti U , KUMAR N R, KAUR, J AND KAUR, R*

ABSTRACT
Bee pollen and propolis are the medicinal and health promoting products of apiculture. The present study investigates the protective role of bee pollen and propolis against anti- tuberculosis drugs (Rifampicin and Isoniazid) in Sprague Dawley Rats by analysing the catalase (CAT) activity. Male SD rats were segregated randomly into twelve groups n=6 for 30 days treatment. The activity of catalase (CAT), in rifampicin treated, isoniazid treated and both the drugs administered in combination, was reduced in the liver, kidney and testis tissues as compared to control groups. The results indicated that co-administration of bee pollen and bee propolis with drugs helped to modulate the toxic effects caused by drugs by restoring tested values to near normal. Keywords: Bee pollen, propolis, catalase, drug, antituberculosis
Publication date: 01/03/2025
    https://ijbpas.com/pdf/2025/March/MS_IJBPAS_2025_8661.pdf
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https://doi.org/10.31032/IJBPAS/2025/14.3.8661