AMELIORATIVE EFFECT OF BEE POLLEN AND BEE PROPOLIS ON CATALASE ACTIVITY AGAINST ANTITUBERCULOSIS DRUGS RIFAMPICIN AND ISONIAZID IN SPRAGUE DAWLEY RATS Authors: Bharti U , KUMAR N R, KAUR, J AND KAUR, R*
ABSTRACT
Bee pollen and propolis are the medicinal and health promoting products of apiculture. The
present study investigates the protective role of bee pollen and propolis against anti-
tuberculosis drugs (Rifampicin and Isoniazid) in Sprague Dawley Rats by analysing the
catalase (CAT) activity. Male SD rats were segregated randomly into twelve groups n=6 for 30
days treatment. The activity of catalase (CAT), in rifampicin treated, isoniazid treated and both
the drugs administered in combination, was reduced in the liver, kidney and testis tissues as
compared to control groups. The results indicated that co-administration of bee pollen and bee
propolis with drugs helped to modulate the toxic effects caused by drugs by restoring tested
values to near normal.
Keywords: Bee pollen, propolis, catalase, drug, antituberculosis Publication date: 01/03/2025 https://ijbpas.com/pdf/2025/March/MS_IJBPAS_2025_8661.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2025/14.3.8661