ABSTRACT

Nanoemulgel is a new and promising drug delivery system employed in the pharmaceutical industry, with droplet diameters ranging from 10 to 100 nm, it is a stable dispersion consisting of an oil, surfactant, and clear aqueous phase that can be stable either thermodynamically or kinetically. the usage of nanoemulgel as a new transdermal drug delivery technique has grown because of its advantages over its existing oral and topical drug delivery methods, including its ability to prevent poor drug bioavailability and phramacokinetic variability. the Novel technique developed by adding nano-emulsion with gel improves stability and permits fast, controlled drug release. the nanoemulgel drug delivery system is a formulation-related technology designed to enhance drug absorption and lipophilic drug therapeutic profile. a significant growth in nanoemulgel has been noted in recent years owing to the high toleration of the formulation to the patients, the application of nanoemulgel has grown recently as a result of the preparation’s enhanced patient acceptance since it is non greasy, easy application, convenient spreadability and has a favourable safety and therapeutic profile. nanoemulgel, despite facing challenges, has a strong potential to become the primary topical administration method for lipophilic drugs in the future. Keywords: Nanoemulsion, Nanoemulgel, topical drug delivery, lipophilic, In vitro profile
Publication date: 01/02/2025

https://ijbpas.com/pdf/2025/February/MS_IJBPAS_2025_8650.pdf

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https://doi.org/10.31032/IJBPAS/2025/14.2.8650