ABSTRACT

The research work investigates the synthesis, spectroscopic characterization, thermal analysis, and in vitro antibacterial activity of Cu(II) transition metal complexes. The metal complexes were synthesized by reacting the respective 4-acyl pyrazolone based ligands. Synthesized ligands were characterized by 1H NMR, Mass, IR, and elemental analysis, while their respective complexes were characterized by IR and elemental analysis. Moreover, thermal studies like TGA, DTG and DSC were also carried. The results confirmed that synthesized Cu(II) metal complexes have promising antibacterial activity against Gram-positive (Bacillus megaterium) and Gram-negative (E.coli) microorganisms, which makes them potential candidates for the development of new antibacterial agents. Keywords: Cu(II) complexes, Schiff base, Acyl Pyrazolone, Thermal studies and antibacterial activity
Publication date: 01/12/2024

https://ijbpas.com/pdf/2024/December/MS_IJBPAS_2024_8475.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.12.8475