ABSTRACT

Gastrointestinal helminths are common infectious agents in human and animals causing anorexia, anemia, diarrhoea and heavy production losses. The important gastro-intestinal helminth parasites belong to three different classes, nematode (roundworm), trematode and cestodes (flatworm). Plants that act as anthelmintics have historically been used to treat parasite illnesses. Costus igneus, sometimes referred to as Spiral flag, is a plant that was recently imported to India from South and Central America. Plants that act as anthelmintics have historically been used to treat parasite illnesses. Costus igneus, sometimes referred to as Spiral flag, is a plant that was recently imported to India from South and Central America. It often grows as a decorative plant in southern India, and its leaves are used as a nutritional supplement to treat diabetes mellitus. The current study's objective was to assess costus igneus anthelmintic effectiveness against Pheretima posthuma (earthworm). Methods: The methods outlined were used to evaluate the anthelmintic activity on mature Indian earthworms. Results: Following exposure to methanolic extract at doses of 1.0, 2.0, and 3.0 mg/ml, paralysis was detected at 9.1 ± 0.43, 8.2 ± 0.20, and death at 19.2 ± 0.50, 24.0 ± 0.32, and 26.0 ± 0.42 minutes, respectively. The results indicate that the Methanolic extract of Costus igneus plant has anthelmintic action in terms of dose dependent approach when connected with standard anthelmintic drug Piperzine citrate (10 mg/ml). Paralysis was observed at 4.3 ± 0.29 min and death occurred after 9.4 ± 0.35 min. Keywords: Costus igneus, Gastrointestinal helminths, anthelmintic activity, Falavanoid Content
Publication date: 01/12/2024

https://ijbpas.com/pdf/2024/December/MS_IJBPAS_2024_8405.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.12.8405