FERMENTATIVE PRODUCTION OF ITACONIC ACID BY USING ASPERGILLUS TERREUS
Authors: Jayappa K , CHAKRAPANI I S*, KARUNAKAR P, RAJASEKHAR M, INDIRA PRIYADARSINI A AND SRINIVAS N

ABSTRACT
Aspergillus species were known to be the best species for the production of Itaconic acid. However very little is known about the industrial production of Itaconic acid in India and virtually nothing is known about its production cost analysis. In view of the extensive industrial use of Itaconicacid, the present study was designed to increase the production of Itaconic acid and an attempt was made to optimize the nutrient medium using Aspergillus terreus. Reducing sugars and phosphorus were measured by the DNS method of Miller (1959) as described by Strickland and Parson (1972) respectively. The cost-effective substrates like Jatropha seed cake, ground nut cake, coconut oil cake, glucose, oat meal and corn flour were used as carbon source for the production of Itaconic acid by using locally isolated Aspergillus terreus strain. Gene Bank accession number of submitted nucleotide sequence is JF495477. The highest yield was observed in Jatropha seed cake (13.60 g/lit),followed by Ground nut cake (10.08g/lit), Coconut oil cake (9.17g/lit), Glucose (7.55 g/lit), Oat meal (4.32 g/lit) and Corn flour (3.27 g/lit). Keywords: Aspergillus terreus, Itaconic acid, Fermentation, Methylene succinic acid, Secondary
Publication date: 01/11/2024
    https://ijbpas.com/pdf/2024/November/MS_IJBPAS_2024_8470.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.11.8470