PROTECTIVE ROLE OF EQUISETUM ARVENSE AGAINST PEPTIC ULCER IN MALE ALBINO WISTAR RATS Authors: M. Nagabharathi , KUMAR KE AND SHAIK RB*
ABSTRACT
Ethnographic relevance: Equisetum arvense has been used in the treatment of peptic ulcer.
Aim of Study:
The present study was conducted to evaluate the potential of Equisetum arvense extract in
peptic ulcers and explore its possible mechanism of action.
Material and Methods:
Equisetum arvense peptic ulcer in male albino Wistar rats was used to evaluate the peptic ulcer
activity of Equisetum arvense extract at an oral dose of 150 mg/kg, 300 mg/kg, and 250mg/kg
for 7 days. Identify Catalase, estimation of reduced glutathione (GSH), estimation of nitrate
levels.
Results:
Significant (p < 0.05) reduction in Catalase, estimation of reduced glutathione (GSH),
estimation of nitrate levels. And peptic ulcer score by Equisetum arvense extract. Equisetum
arvense extract has prevented decrease in peptic ulcer.
Conclusion:
Current media information suggests that Equisetum arvense shows protective activity in peptic
ulcer, which may be due to its improved antioxidant and anti-inflammatory activity.
Keywords: Anti-inflammatory activity, Equisetum arvense, Peptic ulcer, Male Albino
Wistar Rats Publication date: 01/11/2024 https://ijbpas.com/pdf/2024/November/MS_IJBPAS_2024_8435.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2024/13.11.8435