PROTECTIVE ROLE OF EQUISETUM ARVENSE AGAINST PEPTIC ULCER IN MALE ALBINO WISTAR RATS
Authors: M. Nagabharathi , KUMAR KE AND SHAIK RB*

ABSTRACT
Ethnographic relevance: Equisetum arvense has been used in the treatment of peptic ulcer. Aim of Study: The present study was conducted to evaluate the potential of Equisetum arvense extract in peptic ulcers and explore its possible mechanism of action. Material and Methods: Equisetum arvense peptic ulcer in male albino Wistar rats was used to evaluate the peptic ulcer activity of Equisetum arvense extract at an oral dose of 150 mg/kg, 300 mg/kg, and 250mg/kg for 7 days. Identify Catalase, estimation of reduced glutathione (GSH), estimation of nitrate levels. Results: Significant (p < 0.05) reduction in Catalase, estimation of reduced glutathione (GSH), estimation of nitrate levels. And peptic ulcer score by Equisetum arvense extract. Equisetum arvense extract has prevented decrease in peptic ulcer. Conclusion: Current media information suggests that Equisetum arvense shows protective activity in peptic ulcer, which may be due to its improved antioxidant and anti-inflammatory activity. Keywords: Anti-inflammatory activity, Equisetum arvense, Peptic ulcer, Male Albino Wistar Rats
Publication date: 01/11/2024
    https://ijbpas.com/pdf/2024/November/MS_IJBPAS_2024_8435.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.11.8435