COMPREHENSIVE INVESTIGATION OF THERMAL AND BIOLOGICAL PROPERTIES OF NOVEL ZN(II) PYRAZOLONE LIGANDS
Authors: Somaiya CP , YADAV DA, DADHANIYA HR, PATEL VJ, PATEL JR AND RAULJI JB

ABSTRACT
This research presents a comprehensive exploration of the thermal and biological properties of newly synthesized Zn(II) complexes derived from pyrazolone ligands. The synthesis of these compounds involved the utilization of various 4-acyl pyrazolones, followed by rigorous characterization using multiple analytical techniques, including 1H NMR, IR, 13C NMR, elemental analysis, and UV spectroscopy for the ligands. Furthermore, the resulting complexes were extensively characterized through elemental analysis, UV spectroscopy, IR spectroscopy, and thermal analysis techniques, including TGA/DTG and DSC. In addition, biological potential of these compounds was evaluated through antibacterial testing. The findings unveiled promising antibacterial properties, underscoring their potential for further exploration in the realm of antimicrobial agents. Keywords: Pyrazalone, Heterocycles, Schiff base ligand, Co-ordination chemistry, Metal Complexes, Antimicrobial Activity
Publication date: 01/11/2024
    https://ijbpas.com/pdf/2024/November/MS_IJBPAS_2024_8432.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.11.8432