ABSTRACT

Phaseolus vulgaris linn (Fabaceae) is commonly known as French beans also known as kidney beans, is a common Indian dish. The effect of oral administration of aqueous and alcoholic extract of Phaseolus vulgaris seeds on calcium oxalate urolithiasis has been studied in Wistar albino rats. On administration of ethylene glycol and ammonium chloride increase in the deposition of calcium and oxalate level in the kidney and increase urinary excretion of calcium, oxalate and phosphate were observed. Treated with aqueous and alcoholic Phaseolus vulgaris linn seeds extract significantly reduced the elevated urinary calcium and oxalate levels. The increased deposition of stone forming constituents in the kidneys of rats was also significantly lowered by being treated with aqueous and alcoholic extracts. The typical medication used was cystone 750mg/kg. Urine, serum, and kidney histopathology analyses were used to gauge the anti-lithiatic activity. According to the findings, Phaseolus vulgaris linn seeds possess antiurolithiatic action. Keywords: Phaseolus vulgaris, Urolithiasis, Ethylene glycol, Ammonium chloride, Cystone
Publication date: 01/11/2024

https://ijbpas.com/pdf/2024/November/MS_IJBPAS_2024_8400.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.11.8400