ABSTRACT

Organic food consumption has been associated with reduced prevalence and complications of non-communicable diseases. There are limited studies on the therapeutic benefits of organically grown arrowroot in Kerala which can be the powerhouse of therapeutic benefits. Arrowroot (Maranta arundinacea. L) is a carbohydrate-rich plant with potential therapeutic properties. This study aimed to assess the antioxidant, anti-diabetic, antibacterial, and anti-cancer potential of organically grown arrowroot powder by subjecting it to GC-MS analysis, DPPH assay, FRAP assay, agar well diffusion method, alpha amylase inhibition assay and MTT assay. The presence of bioactive compounds in arrowroot powder were identified through GC-MS analysis. Quantitative analysis revealed the presence of phenols and flavonoids. DPPH radical scavenging activity and FRAP assay conducted on the sample showed a concentration-dependent increase, with a maximum activity of 33.16±3.618 percent at 150 ?g/mL of arrowroot powder in DPPH assay and 81.86±1.45 percent at 30 ?g/mL for FRAP assay. In vitro antibacterial activity demonstrated limited effectiveness against Escherichia coli at different concentrations of the sample. In vitro antidiabetic activity revealed maximum inhibition of alpha-amylase (37.21±0.56 percent) at 150 ?g/mL of arrowroot powder. Alpha amylase inhibition activity increased with increasing concentration of arrowroot powder, indicating its potential anti-diabetic property. In vitro cytotoxicity by MTT assay exhibited concentration-dependent effects, with a maximum inhibition of 39.55±1.77 percent observed at 100 ?g/mL against lung cancer cells. The presence of bioactive compounds and the demonstrated therapeutic activities highlight the potential of organically grown arrowroot powder as a functional food ingredient with health benefits. Keywords: Non communicable diseases, antioxidant, antibacterial, antidiabetic, cytotoxicity, therapeutic
Publication date: 01/11/2024

https://ijbpas.com/pdf/2024/November/MS_IJBPAS_2024_8308.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.11.8308