ABSTRACT

Standard oral drug delivery systems encounter many challenges in the gastrointestinal tract, including inefficient drug release and decreased effectiveness of the dose administered. Many efforts have been undertaken to increase medicine's efficacy and bioavailability. Drugs delivered through the buccal mucosa of the oral cavity are called buccal medication drug delivery systems. In pediatric and geriatric patients, buccal films are more effective, since they reduce the frequency of dose administration, ensures plasma peak values, reduce side effects, and make drugs with high first-pass metabolism more affordable. This review outlines the composition, formulation, formulation technologies, buccal film packaging, and future prospect related to the fast dissolving drug delivery system. Key words: Buccal film, Polymer, Solvent Casting, Swelling index, Folding endurance, Bioavailability
Publication date: 01/10/2024

https://ijbpas.com/pdf/2024/October/MS_IJBPAS_2024_8406.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.10.8406