OVERVIEW OF ANALYTICAL TECHNIQUES ON TENELIGLIPTIN HYDROBROMIDE HYDRATE, PIOGLITAZONE HYDROCHLORIDE, METFORMIN HYDROCHLORIDE AND THEIR COMBINATIONS Authors: Patel PH* And Sharma P
ABSTRACT
This study's objective is to offer an in-depth overview of the various analytical procedures used
to determine Teneligliptin Hydrobromide Hydrate, Metformin Hydrochloride, Pioglitazone
Hydrochloride, and their combinations in marketed formulations. This study contains UV, RP-
HPLC, TLC, and other procedures that have been reported to date. Teneligliptin Hydrobromide
Hydrate is approved as monotherapy or with other oral hypoglycaemic medicines (e.g.,
metformin, pioglitazone, sulfonylureas, glinides, and glucosidase inhibitors). Pioglitazone
Hydrochloride is a thiazolidinedione that improves the body's sensitivity to insulin. Metformin
Hydrochloride is a biguanide that reduces sugar production and absorption in your body while
improving the usage of current insulin. They work in tandem to improve blood sugar control.
This review summarizes the studies done on the medications indicated above, either alone or
in combination with or without the presence of contaminants.
Keywords: Anti- diabetic, Teneligliptin Hydrobromide Hydrate, Metformin
Hydrochloride, HPLC, UV Publication date: 01/10/2024 https://ijbpas.com/pdf/2024/October/MS_IJBPAS_2024_8397.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2024/13.10.8397