ABSTRACT

In the gastrointestinal system, itopride hydrochloride1 (ITH) stimulates or promotes motility. By operating as a dopamine D2 receptor antagonist, it boosts the release of acetylcholine (Ach), which stimulates gastrointestinal motility. It minimally raises prolactin levels, does not lengthen the Q-T interval, and cannot cross the blood-brain barrier due to its high polarity, hence it does not result in any CNS-related adverse drug reactions
Publication date: 01/10/2024

https://ijbpas.com/pdf/2024/October/MS_IJBPAS_2024_8377.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.10.8377