MECHANISM OF ACTION AND DENTAL IMPLICATIONS OF SUDANTHA EXTRACT
Authors: Sachdev M , TIRUPATHI SP, AFNAN L, LEKHWANI P4*, NAIR S AND GODBOLE N

ABSTRACT
Sudantha extract (SUD) has gained immense popularity among the researchers in the field of dental medicine. It has shown to exhibit antibacterial, antioxidant, antifungal, antiplasmodial and anti- inflammatory effects. Various components of this extract function by inhibiting major bacterial virulence factors, suppression of gtf genes and inhibition of expression of pro-inflammatory cytokines and IL-8. SUD containing herbal toothpaste has been found beneficial in improving oral hygiene; reducing gingival inflammation, bleeding, plaque accumulation etc. However, more evidence and clinical trials are required to validate their use amongst the human population. Keywords: Sudantha extract, dental uses, herbal medicine, oral hygiene, gingivitis, anti-bacterial, anti- inflammatory effect
Publication date: 01/09/2024
    https://ijbpas.com/pdf/2024/September/MS_IJBPAS_2024_8330.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.9.8330