MECHANISM OF ACTION AND DENTAL IMPLICATIONS OF SUDANTHA EXTRACT Authors: Sachdev M , TIRUPATHI SP, AFNAN L, LEKHWANI P4*, NAIR S AND GODBOLE N
ABSTRACT
Sudantha extract (SUD) has gained immense popularity among the researchers in the field of dental
medicine. It has shown to exhibit antibacterial, antioxidant, antifungal, antiplasmodial and anti-
inflammatory effects. Various components of this extract function by inhibiting major bacterial virulence
factors, suppression of gtf genes and inhibition of expression of pro-inflammatory cytokines and IL-8. SUD
containing herbal toothpaste has been found beneficial in improving oral hygiene; reducing gingival
inflammation, bleeding, plaque accumulation etc. However, more evidence and clinical trials are required
to validate their use amongst the human population.
Keywords: Sudantha extract, dental uses, herbal medicine, oral hygiene, gingivitis, anti-bacterial, anti-
inflammatory effect Publication date: 01/09/2024 https://ijbpas.com/pdf/2024/September/MS_IJBPAS_2024_8330.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2024/13.9.8330