ABSTRACT

This review gives an overview of the different developed analytical methods and spectroscopic methods of Rosuvastatin calcium and Bempedoic acid in their combination with other drugs. The review implies different analytical methods like RP-HPLC, HPLC-UV, RP-UPLC, UV-VIS, and other methods reported to date. Rosuvastatin calcium belongs to the statin class of 3-hydroxy-3-methylglutaryl coenzyme A (HMG- CoA) reductase inhibits. This medicine is used for the treatment of dyslipidemia and can help to reduce the level of "bad cholesterol" as well as the growth of atherosclerosis and the risk of heart disease. Bempedoic acid is a new lipid-lowering drug with a unique mechanism of action Bempedoic acid is used to cure heterozygous familial hypercholesterolemia and heart diseases and to lower cholesterol levels. Rosuvastatin calcium and Bempedoic acid are fixed-dose combinations and are significantly used to treat high cholesterol levels. This review provides a Summary of Work done on Rosuvastatin calcium and bempedoic acid alone or combined with other pharmaceutical drugs. Keywords: HPLC, HPTLC, UV, Rosuvastatin calcium, Bempedoic acid
Publication date: 01/09/2024

https://ijbpas.com/pdf/2024/September/MS_IJBPAS_2024_8327.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.9.8327