HARNESSING OF STIMULI-RESPONSIVE POLYMERS TO OVERCOME THE CHALLENGES OF DRUG DELIVERY
Authors: Cherian MC , SHARMA PK*, DWIVEDI S, GUPTA A AND DARWHEKAR GN

ABSTRACT
Smart polymers that are also known as intelligent polymers or stimuli-responsive polymers have gained an interest in researchers due to its ability to deliver the drug at an appropriate time to an appropriate site under specific physiological condition. These polymers produces its action in response to the stimuli like temperature, pH, light, magnetic field, electric field and many more. Due to this reason, stimuli-responsive polymers are distinct from other conventional formulations. Many advantages are associated to smart polymers which have attracted the attention of the researchers such as ability to release the drug to particular site in a particular manner, but, due to their slow responsive behavior to certain stimuli and less clinical data, impedes the growth of smart polymers. Utilization of polymer based nano- structures (liposomes, niosomes etc.) can contribute in delivering the drug to the target site thus reducing the chances of toxicity. Therefore, this review article focuses on the types of smart polymers, advantages and disadvantages, application in the medical field, challenges of drug delivery through smart polymers and the future prospects of stimuli responsive polymers. Keywords: Intelligent polymer, stimuli-responsive polymer, smart polymer, nano-structures
Publication date: 01/09/2024
    https://ijbpas.com/pdf/2024/September/MS_IJBPAS_2024_8021.pdf
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https://doi.org/10.31032/IJBPAS/2024/13.9.8021