ABSTRACT

Background: Phytochemical analysis is very crucial for drug discovery, development of novel therapeutic agents and to screen presence of any new bioactive compounds in plant derived substances. Also, globally, majority of population still depends on herbal remedies and Michelia champaca (MC) is a well-known ethnopharmacological herb in Ayurveda and exhibits a wide range of therapeutic potential. Objective: The aim and objective of this study was to study the phytochemical profile of ethanolic extract of MC by Gas Chromatography Liquid Chromatography (GC-MS) analysis. Materials and Methods: Ethanolic extract of MC was prepared by soxhlet extraction method and the extract was subjected to GC-MS analysis (Agilent 7890A GC system) for chemical characterization of the extract. The constituents were analysed by matching mass spectra with MS libraries. Results: Total 21 compounds were identified in the extract. The important constituents belonging to phytochemical class - sugar alcohol (Erythritol), sesquiterpenes (caryophyllene oxide), long chain fatty acids (hexadecanoic acid; octadecanoic acid; 8,11-14-eicosatrienoic acid; docosanoic acid, ethyl ester etc.), glucosinolate (Desulphosinigrin), acyclic diterpenoid (phytol), phytosterol (?-sitosterol), sesquiterpene alcohol (2,6,10-Dodecatrien-1-ol,3,7,11-trimethyl-(E,E) etc. were identified in this analysis. Conclusion: Results concluded that the plant has shown to be a potential source of bioactive compounds of significant importance in pharmacology. The researchers would isolate the constituent/s from this plant and can work with different animal or in-vitro models. Keywords: GC-MS, Michelia champaca, Phytoconstituents, Pharmacological, Desulphosinigrin
Publication date: 01/08/2024

https://ijbpas.com/pdf/2024/August/MS_IJBPAS_2024_8230.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.8.8230