ABSTRACT

The present study reveals that the biosynthesized ZnO NPs from the flower extract of Ziziphus mauritiana with ethanol as a solvent when examined for antioxidant activity using dpph scavenging studies and anticariogenic activity with the help of disc diffusion method. The ethanolic flower extract confirmed the presence of terppenoids, flavonoids, saponins, tannins, alkaloids, steroids, glycosides, phlobatannins, protein, coumarin, emodin, antraquinone, anthocyanin, carbohydrate, leucoanthocyanin, cardiac glycoside, xanthoprotein, phenolics. The characterization of synthesized ZnO NPs was observed using the FTIR analysis was used to confirm the functional group involved in reduction of Zn2+ ions, XRD analysis to know the crystallographic structure of nanoparticles involved and SEM analysis to evaluate the morphology of the synthesized ZnO NPs. The anticariogenic activity of synthesized ZnO NPs from the flower of Ziziphus mauritiana exhibited a maximum zone of inhibition for streptococcus sobrinus with the radius of 13.5 mm at a higher concentration of 100 ?g/ml. The antioxidant activity of the synthesized ZnO NPs revealed a maximum inhibition of 84.821% when compared to the standard ascorbic acid (92.857%) at a higher concentration of 100 ?g/ml. Thus it is proposed that the synthesized ZnO NPs from the ethanoilc flower extract of Ziziphus mauritiana acted as a potential source for anticariogenic activity in dental carries application and played an effective role as antioxidant agent. Keywords: Antioxidant And Anticariogenic Activity, Synthesized Zinc Nanoparticles, Ziziphus mauritiana
Publication date: 01/07/2024

https://ijbpas.com/pdf/2024/July/MS_IJBPAS_2024_8195.pdf

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https://doi.org/10.31032/IJBPAS/2024/13.7.8195